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BDBM50456978 CHEMBL4211159

SMILES: Nc1nc(\C=C\CNC(=O)c2cccnc2)c[nH]1

InChI Key: InChIKey=WWPFVCYALHBPCA-DUXPYHPUSA-N

Data: 1 IC50

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Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456978   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50456978
PNG
(CHEMBL4211159)
Show SMILES Nc1nc(\C=C\CNC(=O)c2cccnc2)c[nH]1
Show InChI InChI=1S/C12H13N5O/c13-12-16-8-10(17-12)4-2-6-15-11(18)9-3-1-5-14-7-9/h1-5,7-8H,6H2,(H,15,18)(H3,13,16,17)/b4-2+
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MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



University of Ljubljana

Curated by ChEMBL


Assay Description
Inhibition of human Kv1.3 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method


Eur J Med Chem 139: 232-241 (2017)


Article DOI: 10.1016/j.ejmech.2017.08.015
BindingDB Entry DOI: 10.7270/Q2668GT4
More data for this
Ligand-Target Pair