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BDBM50458169 Avagacestat::BMS 708163::BMS-708163::BMS-708163-01::BMS-70816301

SMILES: NC(=O)[C@@H](CCC(F)(F)F)N(Cc1ccc(cc1F)-c1ncon1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=XEAOPVUAMONVLA-UHFFFAOYSA-N

Data: 4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50458169
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Presenilin-1 (Human)	BDBM50458169 (Avagacestat \| BMS 708163 \| BMS-708163 \| BMS-708163...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.270	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Presenilin-1 (Human)	BDBM50458169 (Avagacestat \| BMS 708163 \| BMS-708163 \| BMS-708163...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.225	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Presenilin-1 (Human)	BDBM50458169 (Avagacestat \| BMS 708163 \| BMS-708163 \| BMS-708163...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Presenilin-1 (Human)	BDBM50458169 (Avagacestat \| BMS 708163 \| BMS-708163 \| BMS-708163...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair