BDBM50458802 CHEMBL4215228

SMILES CS[C@]1(CCN(CC(=O)N2CCN(CC2)c2ccc(cc2)-c2ncccn2)C1)C(=O)Nc1ccc2[nH]nc(-c3ccc(F)cc3)c2c1

InChI Key InChIKey=MRHUCFAJTNKMCG-DHUJRADRSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50458802   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50458802(CHEMBL4215228)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of ERK2 (unknown origin) using peptide substrate measured after 45 mins by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50458802(CHEMBL4215228)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50458802(CHEMBL4215228)
Affinity DataIC50:  25nMAssay Description:Inhibition of ERK1 (unknown origin) using peptide substrate measured after 45 mins by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB