BDBM50459091 ABL-001::ABL001::ABL001-NX::Asciminib::NVP-ABL001::US11649218, Example ABL-001

SMILES: O[C@@H]1CCN(C1)c1ncc(cc1-c1cc[nH]n1)C(=O)Nc1ccc(OC(F)(F)Cl)cc1

InChI Key: InChIKey=VOVZXURTCKPRDQ-UHFFFAOYSA-N

Data: 7 IC50  2 Kd  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50459091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Human)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
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Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Human)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.130	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.90	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50459091 (ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair