BDBM50459149 CHEMBL4213036

SMILES Clc1ccc(Cl)c(CN2CCOC[C@H]2C(=O)N2CCN(C3CC3)c3ccccc23)c1

InChI Key InChIKey=WBXFAFRKSJCJRC-QFIPXVFZSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50459149   

TargetG-protein coupled bile acid receptor 1(Mus musculus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50459149(CHEMBL4213036)
Affinity DataEC50:  316nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50459149(CHEMBL4213036)
Affinity DataEC50:  251nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed