BDBM50464606 CHEMBL4277900::US11091476, Example 17

SMILES: CN1CCC(CC1)c1ccc(Nc2ncc(F)c(n2)-c2cc3c(N=C(C)C33CCCC3)c(F)c2)nc1

InChI Key: InChIKey=AEFFENQISAXIKE-UHFFFAOYSA-N

Data: 21 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50464606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 14 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 1 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	38.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G1/S-specific cyclin-D3 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-E1 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.62	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	38.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G1/S-specific cyclin-D3 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G1/S-specific cyclin-D3 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3 (Human)	BDBM50464606 (CHEMBL4277900 | US11091476, Example 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair