BDBM50464926 CHEMBL4288572

SMILES NC(=O)c1cc(F)cc2[nH]c(-c3cc4c(o3)CNCC4)nc12

InChI Key InChIKey=BLVQSAHMDXWBNC-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50464926   

TargetPoly [ADP-ribose] polymerase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464926BDBM50464926(CHEMBL4288572)
Affinity DataIC50: 144nMAssay Description:Inhibition of recombinant human PARP2 using histone as substrate after 1.5 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464926BDBM50464926(CHEMBL4288572)
Affinity DataKd:  180nMAssay Description:Binding affinity to PARP1 (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464926BDBM50464926(CHEMBL4288572)
Affinity DataIC50: 244nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed