BDBM50464958 CHEMBL4279971

SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NC(c1ccccc1)c1ccccc1

InChI Key InChIKey=PTBSOPAPZKMBJQ-GZBSRTKYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50464958   

TargetProteasome subunit beta type-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464958(CHEMBL4279971)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta-1 using Z-LLE-betaNA as substrate incubated for 15 mins measured for 45 mins by fluorescence ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464958(CHEMBL4279971)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human 20S immunoproteasome beta-5 using Suc-LLVY-AMC as substrate incubated for 15 mins measured for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464958(CHEMBL4279971)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human 20S immunoproteasome beta-1 using Ac-PAL-AMC as substrate incubated for 15 mins measured for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464958(CHEMBL4279971)
Affinity DataIC50:  1.74E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5 using Suc-LLVY-AMC as substrate incubated for 15 mins measured for 45 mins by fluorescence ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed