BDBM50465297 CHEMBL4283230

SMILES CC1(C(=O)Nc2cc(c(cc2O1)NS(=O)(=O)c3cc(ccc3OC)Br)OC)C

InChI Key InChIKey=BVPMJOFBUGYDAV-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465297   

TargetBromodomain-containing protein 4(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50465297(CHEMBL4283230)
Affinity DataKd:  302nMAssay Description:Binding affinity to human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells by isothermal titration calorime...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50465297(CHEMBL4283230)
Affinity DataIC50: 690nMAssay Description:Inhibition of human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells using H-SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed