BDBM50465586 CHEMBL4294174::US10501466, Example B14
SMILES COc1cc(ccc1C)C(=O)N[C@@H]1CCCc2ccc(cc12)-c1cn2CCCc2n1
InChI Key InChIKey=HMOMQPHKMPWUKJ-OAQYLSRUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50465586
Affinity DataKi: 9.40nMAssay Description:Binding affinity to N-terminal 6x-His-SUMO tagged WDR5 delta23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
Affinity DataKi: 26.8nMAssay Description:A fluorescence polarization anisotropy (FPA) assay that measures the displacement of either a FITC-labeled MLL-derived peptide or a more potent 10mer...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity to N-terminal 6x-His-SUMO tagged WDR5 delta23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human WDR5 (22 to 334 residues) assessed as reduction in WRAD-mediated human MLL1 ( 3745 to 3969 residues) H3K4 methylation using human...More data for this Ligand-Target Pair