BDBM50466848 CHEMBL4283751

SMILES N=C1NC(=O)\C(S1)=C\c1ccc2OCCc2c1

InChI Key InChIKey=GRHRWVRWLAIBGN-POHAHGRESA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50466848   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50466848(CHEMBL4283751)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human recombinant full length N-terminal GST-tagged DYRK1A expressed in baculovirus expression system using DYRKtide-F as substrate aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50466848(CHEMBL4283751)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant full length N-terminal GST-tagged DYRK1B expressed in baculovirus expression system using DYRKtide-F as substrate aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50466848(CHEMBL4283751)
Affinity DataIC50:  22nMAssay Description:Inhibition of human full length recombinant CLK1 expressed in baculovirus by measuring substrate phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50466848(CHEMBL4283751)
Affinity DataIC50:  68nMAssay Description:Inhibition of human full length recombinant CLK2 expressed in baculovirus by measuring substrate phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50466848(CHEMBL4283751)
Affinity DataIC50:  7.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))TBA
LigandPNGBDBM50466848(CHEMBL4283751)
Affinity DataIC50:  116nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50466848(CHEMBL4283751)
Affinity DataIC50:  22nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50466848(CHEMBL4283751)
Affinity DataIC50:  6.80E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))TBA
LigandPNGBDBM50466848(CHEMBL4283751)
Affinity DataIC50:  116nMAssay Description:Inhibition of human full length recombinant CLK3 expressed in baculovirus by measuring substrate phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed