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BDBM50467465 CHEMBL4292792

SMILES: Oc1ccc2c(occ(-c3ccc(Cl)c(Cl)c3)c2=O)c1O

InChI Key: InChIKey=MXWFXWNQMIWSCW-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467465   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50467465
PNG
(CHEMBL4292792)
Show SMILES Oc1ccc2c(occ(-c3ccc(Cl)c(Cl)c3)c2=O)c1O
Show InChI InChI=1S/C15H8Cl2O4/c16-10-3-1-7(5-11(10)17)9-6-21-15-8(13(9)19)2-4-12(18)14(15)20/h1-6,18,20H
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 6.30E+3n/an/an/an/a



Chongqing University

Curated by ChEMBL


Assay Description
Inhibition of PI3Kalpha H1047R mutant (unknown origin) by HTRF assay


Eur J Med Chem 158: 707-719 (2018)


Article DOI: 10.1016/j.ejmech.2018.09.002
BindingDB Entry DOI: 10.7270/Q2PK0JVH
More data for this
Ligand-Target Pair