BDBM50467465 CHEMBL4292792

SMILES: Oc1ccc2c(occ(-c3ccc(Cl)c(Cl)c3)c2=O)c1O

InChI Key: InChIKey=MXWFXWNQMIWSCW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50467465 (CHEMBL4292792) Show SMILES Oc1ccc2c(occ(-c3ccc(Cl)c(Cl)c3)c2=O)c1O Show InChI InChI=1S/C15H8Cl2O4/c16-10-3-1-7(5-11(10)17)9-6-21-15-8(13(9)19)2-4-12(18)14(15)20/h1-6,18,20H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a
Chongqing University Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha H1047R mutant (unknown origin) by HTRF assay				Eur J Med Chem 158: 707-719 (2018) Article DOI: 10.1016/j.ejmech.2018.09.002 BindingDB Entry DOI: 10.7270/Q2PK0JVH
					More data for this Ligand-Target Pair