BDBM50467574 MG-516::MG-91516::MGCD-516::MGCD516::Sitravatinib

SMILES: COCCNCc1ccc(nc1)-c1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c2s1

InChI Key: InChIKey=WLAVZAAODLTUSW-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50467574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Human)	BDBM50467574 (MG-516 | MG-91516 | MGCD-516 | MGCD516 | Sitravati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50467574 (MG-516 | MG-91516 | MGCD-516 | MGCD516 | Sitravati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase receptor UFO (Human)	BDBM50467574 (MG-516 | MG-91516 | MGCD-516 | MGCD516 | Sitravati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50467574 (MG-516 | MG-91516 | MGCD-516 | MGCD516 | Sitravati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50467574 (MG-516 | MG-91516 | MGCD-516 | MGCD516 | Sitravati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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BDNF/NT-3 growth factors receptor (Human)	BDBM50467574 (MG-516 | MG-91516 | MGCD-516 | MGCD516 | Sitravati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM50467574 (MG-516 | MG-91516 | MGCD-516 | MGCD516 | Sitravati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity nerve growth factor receptor (Human)	BDBM50467574 (MG-516 | MG-91516 | MGCD-516 | MGCD516 | Sitravati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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