BDBM50467757 CHEMBL4294285
SMILES Cc1cc(O)c(cc1Cc1cc2CN(CCc2s1)C#N)[C@@H]1O[C@H](CO)[C@@H](F)[C@H](O)[C@H]1O
InChI Key InChIKey=CSNQRNLDJGBNRX-VOFPXKNKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50467757
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair