BDBM50469526 CHEMBL4290311

SMILES OC(CCCCN1CCC(CC1)c1noc2cc(F)ccc12)c1cc2CCN3c2c(CCC3=O)c1

InChI Key InChIKey=HRYKMSOBBFZAAT-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50469526   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469526(CHEMBL4290311)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]-ketanserine from serotonin 5-HT2A receptor in rat brain cortex homogenates incubated for 30 mins by liquid scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469526(CHEMBL4290311)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor in rat striatum homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469526(CHEMBL4290311)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-8-OH-DPAT from serotonin 5-HT1A receptor in rat brain cortex homogenates incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469526(CHEMBL4290311)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-lysergic acid diethylamide from human serotonin 5-HT6 receptor expressed in CHO cell membranes incubated for 30 mins by liquid s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469526(CHEMBL4290311)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]-mesulergine from serotonin 5-HT2C receptor in rat brain cerebral cortex homogenates incubated for 15 mins by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469526(CHEMBL4290311)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]-mepyramine from histamine H1 receptor in guinea pig cerebellum homogenates incubated for 60 mins by liquid scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469526(CHEMBL4290311)
Affinity DataKi:  116nMAssay Description:Displacement of [3H] 7-OH-DPAT from dopamine D3 receptor in rat olfactory tubercle homogenates after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469526(CHEMBL4290311)
Affinity DataKi:  596nMAssay Description:Displacement of [3H]-prazosin from alpha-1 adrenergic receptor in rat cerebral cortex homogenates incubated for 60 mins by liquid scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed