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BDBM50471843 CHEMBL130514

SMILES: CCCc1nc2ccccc2n(Cc2ccccc2)c1=O

InChI Key: InChIKey=HEMLGYFICPYWTH-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50471843   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 4


(Homo sapiens (Human))
BDBM50471843
PNG
(CHEMBL130514)
Show SMILES CCCc1nc2ccccc2n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C18H18N2O/c1-2-8-16-18(21)20(13-14-9-4-3-5-10-14)17-12-7-6-11-15(17)19-16/h3-7,9-12H,2,8,13H2,1H3
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PC cid
PC sid
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PubMed
n/an/a 900n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissue


J Med Chem 41: 4021-35 (1998)


BindingDB Entry DOI: 10.7270/Q2TM7DV3
More data for this
Ligand-Target Pair
Phosphodiesterase 3


(Homo sapiens (Human))
BDBM50471843
PNG
(CHEMBL130514)
Show SMILES CCCc1nc2ccccc2n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C18H18N2O/c1-2-8-16-18(21)20(13-14-9-4-3-5-10-14)17-12-7-6-11-15(17)19-16/h3-7,9-12H,2,8,13H2,1H3
PDB
MMDB

Reactome pathway

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibitory activity against cGMP inhibited Phosphodiesterase 3, isolated from guinea pig ventricular tissue


J Med Chem 41: 4021-35 (1998)


BindingDB Entry DOI: 10.7270/Q2TM7DV3
More data for this
Ligand-Target Pair