BDBM50474842 CHEMBL365404

SMILES: COc1cc(CN(CCc2ccccn2)C(=O)C2CC2c2ccccc2)ccc1OCc1ccccc1

InChI Key: InChIKey=WUCPBGMDXNJIMY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50474842   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase RAF and Dual specificity mitogen-activated protein kinase kinase 1 (Raf/MEK) (Homo sapiens (Human))	BDBM50474842 (CHEMBL365404) Show SMILES COc1cc(CN(CCc2ccccn2)C(=O)C2CC2c2ccccc2)ccc1OCc1ccccc1 Show InChI InChI=1S/C32H32N2O3/c1-36-31-20-25(15-16-30(31)37-23-24-10-4-2-5-11-24)22-34(19-17-27-14-8-9-18-33-27)32(35)29-21-28(29)26-12-6-3-7-13-26/h2-16,18,20,28-29H,17,19,21-23H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Morphochem Inc. Curated by ChEMBL					Assay Description Inhibition of EGF-stimulated Elk1-luciferase reporter assay in HeLa cells				Bioorg Med Chem Lett 14: 3957-62 (2004) Article DOI: 10.1016/j.bmcl.2004.05.048 BindingDB Entry DOI: 10.7270/Q2PZ5CM0
					More data for this Ligand-Target Pair