BDBM50482661 CHEMBL1223765

SMILES CCCCNC1=N\C(=C/c2ccc(c(OC)c2)-n2cnc(C)c2)C(=O)N1[C@H](C)c1ccc(F)cc1

InChI Key InChIKey=NPOTZKGVJBZEPV-JVMBGAFUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50482661   

TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482661(CHEMBL1223765)
Affinity DataIC50:  92nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed