BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM50483552 Lersivirine::UK-453061

SMILES: CCc1c(c(n(n1)CCO)CC)Oc2cc(cc(c2)C#N)C#N

InChI Key: InChIKey=MCPUZZJBAHRIPO-UHFFFAOYSA-N

Data: 1 KI 2 IC50 1 Kd

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50483552
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50483552 (Lersivirine \| UK-453061) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	624	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Reverse transcriptase protein (Human immunodeficiency virus type 1)	BDBM50483552 (Lersivirine \| UK-453061) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	215	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50483552 (Lersivirine \| UK-453061) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50483552 (Lersivirine \| UK-453061) Show SMILES Show InChI	GoogleScholar	UniChem		117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair