BDBM50487466 Acrivastine::BW-825C::Benadryl Allgy Relief Plus Decongest::CHEBI:83168::Semprex

SMILES Cc1ccc(cc1)C(=C/CN1CCCC1)\c1cccc(\C=C\C(O)=O)n1

InChI Key InChIKey=PWACSDKDOHSSQD-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50487466   

TargetHistamine H1 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50487466BDBM50487466(CHEBI:83168 | Acrivastine | BW-825C | Benadryl All...)
Affinity DataKd:  0.0670nMAssay Description:Displacement of [3H]-mepyramine from human histamine H1 receptor expressed in HEK293T cells assessed as dissociation rate constant (Koff) incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistamine H1 receptor(Guinea pig)TBA
LigandChemical structure of BindingDB Monomer ID 50487466BDBM50487466(CHEBI:83168 | Acrivastine | BW-825C | Benadryl All...)
Affinity DataIC50: 6.12E+3nMAssay Description:Inhibition of H1 receptor in Cavia porcellus Hartley (guinea pig) ileum assessed as inhibition of histamine-induced spasms incubated 2 min prior hist...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article