BDBM50489307 CHEMBL1643342
SMILES: [H][C@]1(CC[C@@H](CC1)OC(=O)CCc1cc(OC)c(OC)c(OC)c1)N(C)[C@@H]1CC[C@@H](CC1)OC(=O)c1cc(OC)c(OC)c(OC)c1
InChI Key: InChIKey=JXCYICKXOWATCA-PVCJUVKBSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Multidrug resistance protein 1/Multidrug resistance associated protein 1 (Homo sapiens (Human)) | BDBM50489307![]() (CHEMBL1643342) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Firenze Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human doxorubicin-resistant K562 cells assessed as half maximal increase of pirarubicin accumulation by spectrofluoro... | Bioorg Med Chem 21: 456-65 (2013) Article DOI: 10.1016/j.bmc.2012.11.019 BindingDB Entry DOI: 10.7270/Q2ST7SQM | |||||||||||
More data for this Ligand-Target Pair |