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BDBM50490575 CHEMBL1825209::Caffeoylphenylalanyl-Hydroxamic Acid

SMILES: ONC(=O)C(Cc1ccccc1)NC(=O)\C=C\c1ccc(O)c(O)c1

InChI Key: InChIKey=VOODIHXYCJVUOE-VQHVLOKHSA-N

Data: 1 IC50

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Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490575   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosinase


(Agaricus bisporus (Common mushroom))		BDBM50490575
PNG
(CHEMBL1825209 | Caffeoylphenylalanyl-Hydroxamic Ac...)
Show SMILES ONC(=O)C(Cc1ccccc1)NC(=O)\C=C\c1ccc(O)c(O)c1
Show InChI InChI=1S/C18H18N2O5/c21-15-8-6-13(11-16(15)22)7-9-17(23)19-14(18(24)20-25)10-12-4-2-1-3-5-12/h1-9,11,14,21-22,25H,10H2,(H,19,23)(H,20,24)/b9-7+
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.90E+3n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-DOPA substrate incubated for 10 mins

Bioorg Med Chem Lett 23: 1136-42 (2013)


Article DOI: 10.1016/j.bmcl.2012.10.107
BindingDB Entry DOI: 10.7270/Q29P34KQ
More data for this
Ligand-Target Pair