BDBM50491957 CHEMBL2391742

SMILES FC(F)(F)c1ccc(COc2ccc3COC(=O)c3c2)cc1

InChI Key InChIKey=HSTJKFDGUZMVEG-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50491957   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50491957(CHEMBL2391742)
Affinity DataKi:  0.460nMAssay Description:Competitive inhibition of human recombinant monoamine oxidase-B using kynuramine as substrate by Morrison equation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50491957(CHEMBL2391742)
Affinity DataKi:  0.600nMAssay Description:Competitive inhibition of human recombinant monoamine oxidase-B using kynuramine as substrate by Cheng and Prusoff equation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50491957(CHEMBL2391742)
Affinity DataKi:  0.700nMAssay Description:Competitive inhibition of human recombinant monoamine oxidase-B using kynuramine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50491957(CHEMBL2391742)
Affinity DataIC50:  304nMAssay Description:Inhibition of human recombinant monoamine oxidase-A assessed as kynuramine conversion to 6-hydroxyquinoline after 20 mins by fluorescence spectrophot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50491957(CHEMBL2391742)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant monoamine oxidase-B assessed as kynuramine conversion to 6-hydroxyquinoline after 20 mins by fluorescence spectrophot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed