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BDBM50493408 CHEMBL2425766

SMILES: COc1ccc(C(O)Cc2c(Cl)cncc2Cl)c2cc(nn12)C(F)(F)F

InChI Key: InChIKey=VBFAYOJVHJXVMZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50493408   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50493408
PNG
(CHEMBL2425766)
Show SMILES COc1ccc(C(O)Cc2c(Cl)cncc2Cl)c2cc(nn12)C(F)(F)F
Show InChI InChI=1S/C16H12Cl2F3N3O2/c1-26-15-3-2-8(12-5-14(16(19,20)21)23-24(12)15)13(25)4-9-10(17)6-22-7-11(9)18/h2-3,5-7,13,25H,4H2,1H3
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 39n/an/an/an/an/an/a



Kyorin Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of core catalytic domains PDE4B (unknown origin)


Bioorg Med Chem Lett 23: 5311-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.069
BindingDB Entry DOI: 10.7270/Q20Z7663
More data for this
Ligand-Target Pair