BDBM50494202 CHEMBL3086086

SMILES CNc1cc(ccn1)-c1cccnc1Oc1ccc(Nc2nc3ccc(F)c(F)c3[nH]2)cc1

InChI Key InChIKey=WUBLYECGKVDFTH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50494202   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Amgen

Curated by ChEMBL

LigandBDBM50494202(CHEMBL3086086)Copy SMILESCopy InChI

Affinity DataIC50: 9.70nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 30 mins prior to substrate addition measured after 1 hr by IMAP TR-FR...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/1/2020
Entry Details Article
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