BDBM50496832 CHEMBL1738728

SMILES COc1ccc(cc1)S(=O)(=O)N1Cc2cc(ccc2N(Cc2cncn2C)C[C@H]1Cc1ccccc1)C#N

InChI Key InChIKey=BJWZXDNEKWSGQH-RUZDIDTESA-N

Data  2 IC50

PDB links: 3 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50496832   

LigandPNGBDBM50496832(CHEMBL1738728)
Affinity DataIC50: >9.95E+4nMAssay Description:Inhibition of human GGTase1 in human Burkitt lymphoma (Daudi) cell supernatant using [3H]geranylgeranylMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50496832(CHEMBL1738728)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant FTase using [3H]farnesyldiphosphateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB