BDBM50498980 CHEMBL3734825

SMILES COC1CCN(CC1)c1nccc(Nc2cc3n(cnc3cn2)C2CCCC2)n1

InChI Key InChIKey=HVRZVMCNHMWTOQ-UHFFFAOYSA-N

Data  1 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50498980   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50498980(CHEMBL3734825)
Affinity DataKi:  20nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins followed by addition of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB