BDBM50498988 CHEMBL3735157

SMILES CC(C)n1c(C)nc2cnc(Nc3ccnc(\C=C\C(C)(C)O)n3)cc12

InChI Key InChIKey=NMZMPVANOBBUBA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50498988   

TargetEpidermal growth factor receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50498988(CHEMBL3735157)
Affinity DataKi:  323nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins followed by addition of substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50498988(CHEMBL3735157)
Affinity DataKi: >2.50E+3nMAssay Description:Inhibition of human wild type EGFR using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins followed by addition of substrate measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed