BDBM50499824 CHEMBL3740017

SMILES C[C@H]1Cn2c(nnc2C(F)(F)F)CN1C(=O)c3cccc(c3)C(C4=NNC(=O)c5c4cccc5)(F)F

InChI Key InChIKey=SRNBPLVNLYRSLY-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50499824   

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50499824(CHEMBL3740017)
Affinity DataEC50:  216nMAssay Description:Inhibition of PARP in human HeLa cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed