BDBM50500475 CHEMBL3747244

SMILES [H][C@@]1(CC[C@@H](Cc2ccc(cc2)C(=O)N2CCC3(CCOC3=O)CC2)N1)[C@H](O)c1ccccc1

InChI Key InChIKey=XLZXWDOHDWIAJA-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50500475   

TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500475(CHEMBL3747244)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500475(CHEMBL3747244)
Affinity DataIC50: 5.60E+3nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500475(CHEMBL3747244)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500475(CHEMBL3747244)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed