BDBM50502522 CHEMBL4476351

SMILES FC(F)(F)c1ncncc1-c1nc2ccc(nc2n1C1CC1)C#N

InChI Key InChIKey=NZDLXEGMGVMQKW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502522   

TargetCytochrome P450 11B2, mitochondrial(Human)
Selenity Therapeutics

Curated by ChEMBL
LigandPNGBDBM50502522(CHEMBL4476351)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant CYP11B2 using deoxycorticosterone as substrate incubated for 90 mins by cell-based HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Selenity Therapeutics

Curated by ChEMBL
LigandPNGBDBM50502522(CHEMBL4476351)
Affinity DataIC50: 4.81E+3nMAssay Description:Inhibition of human recombinant CYP11B1 using deoxycortisol as substrate incubated for 60 mins by cell-based HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed