BDBM50502523 CHEMBL4444394

SMILES Fc1cc2nc(-c3cncnc3C3CC3)n(C3CC3)c2cc1F

InChI Key InChIKey=YMIHWHQUKLPPNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502523   

TargetCytochrome P450 11B2, mitochondrial(Human)
Selenity Therapeutics

Curated by ChEMBL
LigandPNGBDBM50502523(CHEMBL4444394)
Affinity DataIC50: 172nMAssay Description:Inhibition of human recombinant CYP11B2 using deoxycorticosterone as substrate incubated for 90 mins by cell-based HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Selenity Therapeutics

Curated by ChEMBL
LigandPNGBDBM50502523(CHEMBL4444394)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP11B1 using deoxycortisol as substrate incubated for 60 mins by cell-based HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed