BDBM50505255 BIIB-074::BIIB074::CNV-1014802::CNV1014802::GSK-1014802::GSK1014802::Raxatrigine::Vixotrigine

SMILES: c1ccc(c(c1)COc2ccc(cc2)[C@H]3CC[C@H](N3)C(=O)N)F

InChI Key: InChIKey=JESCETIFNOFKEU-UHFFFAOYSA-N

Data: 1 KI  22 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50505255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2A6 (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 9 subunit alpha (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 1 subunit alpha (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Amine oxidase [flavin-containing] B (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C8 (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2B6 (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 2 subunit alpha (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 3 subunit alpha (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 8 subunit alpha (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 3 subunit alpha (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 1 subunit alpha (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 10 subunit alpha (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 4 subunit alpha (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 7 subunit alpha (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Amine oxidase [flavin-containing] A (Human)	BDBM50505255 (BIIB-074 | BIIB074 | CNV-1014802 | CNV1014802 | GS...) Show SMILES Show InChI	GoogleScholar	UniChem		<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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