BDBM50506350 Simurosertib::Tak 931::Tak-931

SMILES: Cc1n[nH]cc1-c1cc2nc([nH]c(=O)c2s1)[C@@H]1CC2CCN1CC2

InChI Key: InChIKey=XGVXKJKTISMIOW-UHFFFAOYSA-N

Data: 6 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50506350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM50506350 (Simurosertib | Tak 931 | Tak-931) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Human)	BDBM50506350 (Simurosertib | Tak 931 | Tak-931) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.424	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase/Protein DBF4 homolog A (Human)	BDBM50506350 (Simurosertib | Tak 931 | Tak-931) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM50506350 (Simurosertib | Tak 931 | Tak-931) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Human)	BDBM50506350 (Simurosertib | Tak 931 | Tak-931) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase/Protein DBF4 homolog A (Human)	BDBM50506350 (Simurosertib | Tak 931 | Tak-931) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase/Protein DBF4 homolog A (Human)	BDBM50506350 (Simurosertib | Tak 931 | Tak-931) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair