BDBM50510872 CHEMBL4303404

SMILES Cc1noc2[C@H](CC(N)=O)N=C(c3ccc(Cl)cc3)c3ccccc3-c12

InChI Key InChIKey=GCWIQUVXWZWCLE-INIZCTEOSA-N

Data  21 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50510872   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Taros Chemicals

Curated by ChEMBL
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50:  39nMAssay Description:Inhibition of BRD4 bromodomain-1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 8(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >1.50E+4nMAssay Description:Binding affinity to BRD8 bromodomain (unknown origin) incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Taros Chemicals

Curated by ChEMBL
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50:  3nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Taros Chemicals

Curated by ChEMBL
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50:  39nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 9(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >8.00E+4nMAssay Description:Displacement of biotinylated JQ1 from BRD9 bromodomain (unknown origin) incubated for 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >2.00E+4nMAssay Description:Binding affinity to PCAF bromodomain (unknown origin) incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPeregrin(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >2.00E+4nMAssay Description:Binding affinity to BRPF1 bromodomain (unknown origin) incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 9(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >8.00E+4nMAssay Description:Binding affinity to BRD9 bromodomain (unknown origin) incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCREB-binding protein(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >2.00E+4nMAssay Description:Binding affinity to CBP bromodomain (unknown origin) incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 8(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of biotinylated JQ1 from BRD8 bromodomain (unknown origin) incubated for 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated JQ1 from TRIM24 bromodomain (unknown origin) incubated for 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >8.00E+4nMAssay Description:Displacement of biotinylated JQ1 from ATAD2 bromodomain (unknown origin) incubated for 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription activator BRG1(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated JQ1 from BRG1 bromodomain (unknown origin) incubated for 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated JQ1 from PCAF bromodomain (unknown origin) incubated for 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPeregrin(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated JQ1 from BRPF1 bromodomain (unknown origin) incubated for 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Taros Chemicals

Curated by ChEMBL
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataEC50:  180nMAssay Description:Inhibition of BRD4 BD1 in human MV4-11 cells assessed as reduction of MYC RNA expression after 4 hrs by PCR analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Taros Chemicals

Curated by ChEMBL
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50:  39nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using biotinylated ligand incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCREB-binding protein(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated JQ1 from CBP bromodomain (unknown origin) incubated for 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription activator BRG1(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >2.00E+4nMAssay Description:Binding affinity to BRG1 bromodomain (unknown origin) incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >8.00E+4nMAssay Description:Binding affinity to ATAD2 bromodomain (unknown origin) incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50: >2.00E+4nMAssay Description:Binding affinity to TRIM24 bromodomain (unknown origin) incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Taros Chemicals

Curated by ChEMBL
LigandPNGBDBM50510872(CHEMBL4303404)
Affinity DataIC50:  11nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed