BDBM50511166 CHEMBL4513436

SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(N)nc1

InChI Key InChIKey=HQDQKMVQJREOAX-LWPKXAGOSA-N

Data  1 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511166   

TargetProthrombin(Homo sapiens (Human))
Philipps-University Marburg

Curated by ChEMBL
LigandPNGBDBM50511166(CHEMBL4513436)
Affinity DataKi:  140nMAssay Description:Inhibition of human alpha-thrombin using varying levels of Tos-Gly-Pro-Arg-AMC-TFA as substrate by fluorescence based Michaelis-Menten equation analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Philipps-University Marburg

Curated by ChEMBL
LigandPNGBDBM50511166(CHEMBL4513436)
Affinity DataKd:  400nMAssay Description:Binding affinity to human alpha-thrombin in phosphate/HEPES/Tricine/Tris buffer by ITC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Philipps-University Marburg

Curated by ChEMBL
LigandPNGBDBM50511166(CHEMBL4513436)
Affinity DataKd:  43nMAssay Description:Binding affinity to bovine beta-trypsin in phosphate/HEPES/Tricine/Tris buffer by ITC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed