BDBM50512442 CHEMBL4554856

SMILES CC(C)N1Cc2cc(O[C@@H](C)CNC(=O)c3cnn4cc1cnc34)cc(F)c2Cl

InChI Key InChIKey=JHUWBOAVDAIILQ-LBPRGKRZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50512442   

TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50512442(CHEMBL4554856)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50512442(CHEMBL4554856)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant full length human TRKA expressed in U2OS cells using Poly(Glu:Tyr) as substrate after 30 mins by scintillation counting ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50512442(CHEMBL4554856)
Affinity DataIC50:  0.536nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed