BDBM50514402 CHEMBL4535757::US11345701, Compound Amg-510

SMILES: CC(C)c1nccc(C)c1-n1c2nc(c(F)cc2c(nc1=O)N1CCN(C[C@@H]1C)C(=O)C=C)-c1c(O)cccc1F

InChI Key: InChIKey=NXQKSXLFSAEQCZ-UHFFFAOYSA-N

Data: 2 KI  6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50514402   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GTPase KRas [G12C] (Human)	BDBM50514402 (CHEMBL4535757 | US11345701, Compound Amg-510) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24.5	n/a	n/a	n/a	n/a	n/a	n/a
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GTPase KRas (Human)	BDBM50514402 (CHEMBL4535757 | US11345701, Compound Amg-510) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
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GTPase KRas (Human)	BDBM50514402 (CHEMBL4535757 | US11345701, Compound Amg-510) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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GTPase KRas (Human)	BDBM50514402 (CHEMBL4535757 | US11345701, Compound Amg-510) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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GTPase KRas (Human)	BDBM50514402 (CHEMBL4535757 | US11345701, Compound Amg-510) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
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GTPase KRas (Human)	BDBM50514402 (CHEMBL4535757 | US11345701, Compound Amg-510) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<7	n/a	n/a	n/a	n/a	n/a	n/a
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GTPase KRas (Human)	BDBM50514402 (CHEMBL4535757 | US11345701, Compound Amg-510) Show SMILES Show InChI	GoogleScholar	UniChem		1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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GTPase KRas (Human)	BDBM50514402 (CHEMBL4535757 | US11345701, Compound Amg-510) Show SMILES Show InChI	GoogleScholar	UniChem		8.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair