BDBM50527304 CHEMBL4560554::US10829446, Compound 113

SMILES CCCOc1cc(c(c(c1)C(=O)NNS(=O)(=O)c2ccccc2)F)C

InChI Key InChIKey=GOFZTZBCDBZRIA-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527304   

TargetHistone acetyltransferase KAT6A [507-778](Human)
Monash University

US Patent
LigandPNGBDBM50527304(CHEMBL4560554 | US10829446, Compound 113)
Affinity DataIC50: 52nMAssay Description:Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
Monash University

US Patent
LigandPNGBDBM50527304(CHEMBL4560554 | US10829446, Compound 113)
Affinity DataIC50: 52nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed