BDBM50527778 KPT-330::Selinexor::US20240376114, Compound 70::Xpovio

SMILES: FC(F)(F)c1cc(cc(c1)C(F)(F)F)-c1ncn(\C=C/C(=O)NNc2cnccn2)n1

InChI Key: InChIKey=DEVSOMFAQLZNKR-UHFFFAOYSA-N

Data: 3 IC50  1 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50527778   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Rev (Human immunodeficiency virus type 1)	BDBM50527778 (KPT-330 | Selinexor | Xpovio | US20240376114, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Exportin-1 (Human)	BDBM50527778 (KPT-330 | Selinexor | Xpovio | US20240376114, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Exportin-1 (Human)	BDBM50527778 (KPT-330 | Selinexor | Xpovio | US20240376114, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Exportin-1 (Human)	BDBM50527778 (KPT-330 | Selinexor | Xpovio | US20240376114, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Exportin-1 (Human)	BDBM50527778 (KPT-330 | Selinexor | Xpovio | US20240376114, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair