BDBM50531784 Fanotaprim::TRC-2533::TRC-2533-NX::US11530198, Example 78::VYR-006

SMILES: COc1ncc(cn1)-c1cccc(c1)N1CCN(CC1)c1cnc(N)nc1N

InChI Key: InChIKey=GUZBZPCNAJDYMO-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50531784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Human)	BDBM50531784 (Fanotaprim | TRC-2533 | TRC-2533-NX | VYR-006 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional dihydrofolate reductase-thymidylate synthase (Toxoplasma gondii)	BDBM50531784 (Fanotaprim | TRC-2533 | TRC-2533-NX | VYR-006 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.24	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Human)	BDBM50531784 (Fanotaprim | TRC-2533 | TRC-2533-NX | VYR-006 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	912	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional dihydrofolate reductase-thymidylate synthase (Trypanosoma brucei brucei)	BDBM50531784 (Fanotaprim | TRC-2533 | TRC-2533-NX | VYR-006 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.09	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50531784 (Fanotaprim | TRC-2533 | TRC-2533-NX | VYR-006 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	912	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50531784 (Fanotaprim | TRC-2533 | TRC-2533-NX | VYR-006 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.708	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50531784 (Fanotaprim | TRC-2533 | TRC-2533-NX | VYR-006 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	308	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Toxoplasma gondii)	BDBM50531784 (Fanotaprim | TRC-2533 | TRC-2533-NX | VYR-006 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair