BDBM50532767 CHEMBL4453878

SMILES COC(=O)Nc1nc2cc(Sc3nnc4ccc(nn34)-c3ccc(F)cc3)ccc2[nH]1

InChI Key InChIKey=GXKYDDNYCCSFKJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50532767   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany

Curated by ChEMBL
LigandPNGBDBM50532767(CHEMBL4453878)
Affinity DataIC50:  10nMAssay Description:Inhibition of wild type phosphorylated MET (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptide ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Sanofi-Aventis Germany

Curated by ChEMBL
LigandPNGBDBM50532767(CHEMBL4453878)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Sanofi-Aventis Germany

Curated by ChEMBL
LigandPNGBDBM50532767(CHEMBL4453878)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany

Curated by ChEMBL
LigandPNGBDBM50532767(CHEMBL4453878)
Affinity DataIC50:  10nMAssay Description:Inhibition of wild type phosphorylated MET (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptide ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed