BDBM50533006 Af-219::Gefapixant::R-1646::R1646::RG-1646::RG1646::RO-4926219::RO4926219::US20240034729, Positive compound 2

SMILES: CC(C)c1cc(c(cc1Oc2cnc(nc2N)N)S(=O)(=O)N)OC

InChI Key: InChIKey=HLWURFKMDLAKOD-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50533006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Human)	BDBM50533006 (Af-219 | Gefapixant | R-1646 | R1646 | RG-1646 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	52.2	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 3 (Human)	BDBM50533006 (Af-219 | Gefapixant | R-1646 | R1646 | RG-1646 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Human)	BDBM50533006 (Af-219 | Gefapixant | R-1646 | R1646 | RG-1646 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Human)	BDBM50533006 (Af-219 | Gefapixant | R-1646 | R1646 | RG-1646 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Human)	BDBM50533006 (Af-219 | Gefapixant | R-1646 | R1646 | RG-1646 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50533006 (Af-219 | Gefapixant | R-1646 | R1646 | RG-1646 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair