BDBM50534288 CHEMBL4472617

SMILES Oc1ccc(cc1)-c1cn(nn1)C1CN2CCC1CC2

InChI Key InChIKey=ZRCMYKLGYHVJGO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50534288   

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50534288(CHEMBL4472617)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK293 cell membranes after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50534288(CHEMBL4472617)
Affinity DataKi:  9.60nMAssay Description:Displacement of [3H]MLA from human alpha7 nAChR transfected in human SH-SY5Y cell membranes after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50534288(CHEMBL4472617)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]MLA from human recombinant alpha7 nAChR expressed in HEKtsA201 cells after 1 hr by CNiFERs binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50534288(CHEMBL4472617)
Affinity DataKi:  627nMAssay Description:Displacement of [3H]epibatidine from human alpha4beta2 nAChR transfected in HEK293 cell membranes after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50534288(CHEMBL4472617)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+/-)-epibatidine from human recombinant alpha4beta2 nAChR expressed in HEKtsA201 cells after 1 hr by CNiFERs binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed