BDBM50535669 CHEMBL1233930
SMILES Nc1nc(O)c2N3[C@@H](CN(C3=O)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2n1
InChI Key InChIKey=JSNFRYBHBVDHSG-NEPJUHHUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50535669
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 663nMAssay Description:Inhibition of His-tagged human MTHFD2 ( 36 to 350 residues) expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before folitixorin and...More data for this Ligand-Target Pair
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Inhibition of His-tagged human MTHFD1 ( 1 to 306 residues) expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before folitixorin and ...More data for this Ligand-Target Pair