BDBM50536817 CHEMBL4587019

SMILES COc1ncc(cc1[N+]([O-])=O)-c1ccc2ncnc(NCCN3CCCCC3)c2c1

InChI Key InChIKey=IRVWQBGEHKMMGH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536817   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Xi'An Jiaotong University

Curated by ChEMBL

LigandBDBM50536817(CHEMBL4587019)Copy SMILESCopy InChI

Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) assessed as reduction in ATP depletion using lipid substrate after 40 mins by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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