BDBM50537722 CHEMBL4643688::US11230547, Compound 1-18

SMILES [H][C@]12CN(c3nc(ncc3C#N)-c3cnc4[nH]ccc4c3)[C@]([H])(CN1c1cccc(F)c1)C2

InChI Key InChIKey=WHKNAESTUDYHFE-PMACEKPBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537722   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50537722(CHEMBL4643688 | US11230547, Compound 1-18)
Affinity DataIC50:  920nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50537722(CHEMBL4643688 | US11230547, Compound 1-18)
Affinity DataIC50:  918nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p110delta/untagged full-length p85alpha expressed in baculovirus infected Sf21 cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed