BDBM50537725 CHEMBL4635168::US11230547, Compound 2-1

SMILES [H][C@]12CN(c3nc(ncc3C#N)-c3cnn(C)c3)[C@]([H])(CN1C(=O)C1CC1)C2

InChI Key InChIKey=BAPNSRDKEKRQFX-GJZGRUSLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50537725   

LigandPNGBDBM50537725(CHEMBL4635168 | US11230547, Compound 2-1)
Affinity DataIC50:  258nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537725(CHEMBL4635168 | US11230547, Compound 2-1)
Affinity DataIC50:  160nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50537725(CHEMBL4635168 | US11230547, Compound 2-1)
Affinity DataIC50:  161nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p110delta/untagged full-length p85alpha expressed in baculovirus infected Sf21 cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed