BDBM50537731 CHEMBL4640567::US11230547, Compound 3-1

SMILES Cn1cc(cn1)-c1ncc(C#N)c(n1)N1CCN(c2cccc(F)c2)C(C)(C)C1

InChI Key InChIKey=LHBOCJIOQYAOLR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537731   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50537731(CHEMBL4640567 | US11230547, Compound 3-1)
Affinity DataIC50:  1.50E+3nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50537731(CHEMBL4640567 | US11230547, Compound 3-1)
Affinity DataIC50:  1.52E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p110delta/untagged full-length p85alpha expressed in baculovirus infected Sf21 cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed