BDBM50537738 CHEMBL4633285::US11230547, Compound 4-8

SMILES C[C@@H]1C[C@H]1C(=O)N1CCN(C[C@H]1C)c1nc(ncc1C#N)-c1cnn(C)c1

InChI Key InChIKey=ZXXHAWWIMOPNIX-XJKCOSOUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50537738   

LigandPNGBDBM50537738(CHEMBL4633285 | US11230547, Compound 4-8)
Affinity DataIC50:  187nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537738(CHEMBL4633285 | US11230547, Compound 4-8)
Affinity DataIC50:  32nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50537738(CHEMBL4633285 | US11230547, Compound 4-8)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p110delta/untagged full-length p85alpha expressed in baculovirus infected Sf21 cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed